Vickro Biopharma Pvt. Ltd.

Analytical Development

Rigorous Characterization & Quality Assurance

PRECISION ANALYTICS

Data-Driven
Decision Making

We employ a "quality by design" (QbD) approach, utilizing state-of-the-art instrumentation to ensure the identity, purity, potency and safety of every product. Our analytical methods are developed and validated to meet global ICH regulatory standards.

ICH Validation
High Resolution
STATUS: ACQUIRING
METHOD: RP-HPLC
RT: 12.45 min

Comprehensive Characterization

Our analytical platform covers the entire spectrum of product attributes ensuring a complete understanding of the molecule.

Physico-Chemical

  • Intact Mass Analysis (LC-MS)
  • Peptide Mapping
  • Glycan Profiling
  • Charge Variant Analysis (CEX)

Purity & Impurities

  • Size Exclusion (SEC-HPLC)
  • Host Cell Protein (HCP) ELISA
  • Residual DNA (qPCR)
  • Endotoxin Testing

Biological Activity

  • Cell-Based Potency Assays
  • Ligand Binding Assays (ELISA/SPR)
  • ADCC / CDC Activity
  • Signal Transduction

Biophysical

  • Circular Dichroism (CD)
  • DSC / DSF
  • Dynamic Light Scattering (DLS)
  • Sub-visible Particles (MFI)

Stability

  • Real-time Stability
  • Accelerated Stress Testing
  • Photostability
  • Freeze-Thaw Cycling

Stress Testing

  • Oxidation
  • Deamidation
  • pH Excursion
  • Agitation